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The Singleton Center

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The Charles Singleton Center for the Study of Pre-Modern Europe
The Johns Hopkins University
Gilman Hall 301
Baltimore, MD 21218

Lawrence Principe
Interim Director

Phone (410) 516-5296
Fax (410) 516-7586


Lawrence Principe

Director, Singleton Center

Drew Professor of the Humanities
Department of the History of Science and Technology

Departmental Page

Office: 376 Gilman Hall
Phone: 410-516-4807

Recent Publications:


The Secrets of Alchemy (Chicago: University of Chicago Press, 2013).

The Scientific Revolution: A Very Short Introduction (Oxford: Oxford University Press, 2011).

The Accademia del Cimento and Its European Context, ed. with Marco Beretta and Antonio Clericuzio (Sagamore Beach, MA: Science History Publications, 2009).

Chymists and Chymistry: Studies in the History of Alchemy and Early Modern Chemistry, ed. (Sagamore Beach, MA: Science History Publications, 2007).

New Narratives in Eighteenth-Century Chemistry, ed. (Dordrecht: Springer, 2007); also includes my paper "A Revolution Nobody Noticed? Changes in Early Eighteenth-Century Chymistry," pp. 1-22.

Alchemy Tried in the Fire: Starkey, Boyle, and the Fate of Helmontian Chymistry. With W. R. Newman (Chicag University of Chicago Press, 2002).

The Aspiring Adept: Robert Boyle and His Alchemical Quest (Princeton, NJ: Princeton U. Press, 1998).


“Sir Kenelm Digby and His Alchemical Circle in 1650s Paris: Newly Discovered
Manuscripts,” Ambix 60 (2013): 3-24.

“John Locke and the Case of Anthony Ashley Cooper,” with Peter Anstey, Early Science and Medicine 16, (2011): 379-503.

"Alchemy Restored," Isis 102 (2011): 305-312.

"Wilhelm Homberg et la chimie de la lumière," Methodos: Savoirs et textes 8 (2008);

“Revealing Analogies: The Descriptive and Deceptive Roles of Sexuality and Gender in Latin Alchemy,” in Hidden Intercourse, ed. Wouter Hanegraaff, (Leiden: Brill, 2008; Fordham Press, 2011).

“Reflections on Newton’s Alchemy in Light of the New Historiography of Alchemy,” pp. 205-19 in Newton and Newtonianism: New Studies, eds. James E. Force and Sarah Hutton, (Dordrecht: Kluwer, 2004).

“Georges Pierre des Clozets, Robert Boyle, the Alchemical Patriarch of Antioch, and the Reunion of Christendom,” Early Science and Medicine 9, (2004):307-20.

"Wilhelm Homberg: Chymical Corpuscularianism and Chrysopoeia in the Early Eighteenth Century," pp. 535-56 in: Late Medieval and Early Modern Corpuscular Matter Theories, eds. C. Luthy, J. E. Murdoch, and W. R. Newman (Leiden: Brill, 2001).

"Some Problems in the Historiography of Alchemy."  With William R. Newman.  Pp. 385-434 in Secrets of Nature: Astrology and Alchemy in Early Modern Europe (Cambridge MA; MIT Press, 2001).

"Apparatus and Reproducibility in Alchemy." Pp. 55-74 in Instruments and Experimentation in the History of Chemistry, eds. Frederic L. Holmes and Trevor Levere, (Cambridge, MA; MIT Press, 2000).

"The Alchemies of Robert Boyle and Isaac Newton: Alternate Approaches and Divergent Deployments." Pp. 201-220 in Rethinking the Scientific Revolution, ed. Margaret J. Osler, (Cambridge: Cambridge U. Press, 2000).

"Alchemy vs. Chemistry: The Etymological Origins of a Historiographic Mistake." With William R. Newman. Early Science and Medicine, 1998, 3:32-65.

Available Audio/Video Courses:

            History of Science: Antiquity to 1700, (thirty-six 30-minute lectures)

            Science and Religion, (twelve 30-minute lectures)

Both are produced and marketed by The Teaching Company, Chantilly, VA,