Lee Lab Publishes Paper in Neuron

The lab of MBI Researcher Hey-Kyoung Lee published a new study online in the journal Neuron, with CMDB graduate student Varun Chokshi as primary author. In collaboration with Paul Worley of the Dept. of Neuroscience, they demonstrated that visual experience-dependent metaplasticity in visual cortex is input-specific and depends on induction of an immediate early gene, Homer1a, and its interaction with metabotropic glutamate receptor 5 (mGluR5).  The title of the paper is “Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling.”