{"id":2007,"date":"2026-02-23T12:31:25","date_gmt":"2026-02-23T17:31:25","guid":{"rendered":"https:\/\/krieger.jhu.edu\/mbi\/?p=2007"},"modified":"2026-03-04T12:39:00","modified_gmt":"2026-03-04T17:39:00","slug":"new-paper-from-the-monosov-laboratory-uncovers-the-circuitry-that-guides-novelty-seeking","status":"publish","type":"post","link":"https:\/\/krieger.jhu.edu\/mbi\/2026\/02\/23\/new-paper-from-the-monosov-laboratory-uncovers-the-circuitry-that-guides-novelty-seeking\/","title":{"rendered":"New paper from the Monosov laboratory uncovers the circuitry that guides novelty seeking"},"content":{"rendered":"\n<p>A paper by Assistant Research Scientist, Takaya Ogasawara and et al, from Ilya Monosov&#8217;s lab have made a discovery on how temporal-orbitofrontal pathway regulates choices across physical reward and visual novelty.<\/p>\n\n\n\n<p>Highlights<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Predictions of future perceptual novelty impact the valuation of primary rewards<\/li>\n\n\n\n<li>Temporal-orbital circuit is causally involved in this process<\/li>\n\n\n\n<li>Temporal cortex is relatively more enriched in neurons signaling novelty prediction<\/li>\n\n\n\n<li>Orbitofrontal cortex is relatively more enriched in neurons reflecting preference<\/li>\n<\/ul>\n\n\n\n<p><a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(25)00938-9\">Temporal-orbitofrontal pathway regulates choices across physical reward and visual novelty<\/a><\/p>\n\n\n\n<p>See associated News &amp; Views article:<\/p>\n\n\n\n<p><a href=\"https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(25)00938-9\">https:\/\/www.cell.com\/neuron\/fulltext\/S0896-6273(25)00938-9<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A paper by Assistant Research Scientist, Takaya Ogasawara and et al, from Ilya Monosov&#8217;s lab have made a discovery on how temporal-orbitofrontal pathway regulates choices across physical reward and visual [&hellip;]<\/p>\n","protected":false},"author":729,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","footnotes":""},"categories":[1],"tags":[79,81],"class_list":["post-2007","post","type-post","status-publish","format-standard","hentry","category-news","tag-monosov","tag-temporal-orbitofrontal-pathway"],"acf":[],"_links":{"self":[{"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/posts\/2007","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/users\/729"}],"replies":[{"embeddable":true,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/comments?post=2007"}],"version-history":[{"count":4,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/posts\/2007\/revisions"}],"predecessor-version":[{"id":2017,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/posts\/2007\/revisions\/2017"}],"wp:attachment":[{"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/media?parent=2007"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/categories?post=2007"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/krieger.jhu.edu\/mbi\/wp-json\/wp\/v2\/tags?post=2007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}