The lab of Alfredo Kirkwood of MBI published a paper in Neuron showing that sleep radically decreases the balance between synaptic excitation and synaptic inhibition in the brain. This finding challenges the traditional view that the excitation/ inhibition balance needs to be stable to allow proper neural function.

https://www.sciencedirect.com/science/article/pii/S0896627319309742?via%3Dihub