Bodian Seminars are scheduled for every Monday at 4 p.m. If there is not a specific date listed below, then that date is open. Please contact us to schedule a seminar for an open date.
Special Seminar: Seung-Hee Lee, Ph.D.
Department of Biological Sciences
Korea Advanced Institute of Science & Technology
Neural circuits for audiovisual integration and perceptual decision
Sensory perception in the real world requires proper integration of different modality inputs under dynamic motor actions. When the mammalian brain receives multisensory information, it is dissociated into modality-specific ones through different channels and integrated via circuits of multisensory integration. The integration process is critical for the generation of a multisensory percept and the transformation into proper actions. The processes of multisensory integration and perceptual decision are not uniform but unique and subjective. It varies from individual to individual and changes at different behavioral states of the animal. In this talk, I will discuss how the cortical circuits integrate audiovisual inputs and generate optimal behaviors in mice. By combining anatomical, physiological and behavioral methods, we have identified two cortical circuits that are important for perceptual decision in mice. First, we identified that the posterior parietal cortex, which receives auditory and visual inputs, plays a critical role in resolving audiovisual conflicts via local inhibitory neurons. Interestingly, locomotion modulates these circuits and tunes the perceptual decision upon the conflicts. Next, we found that the cingulate cortex plays a critical role in controlling vision-guided action via receiving visual inputs and relieving motor inhibition. Collectively, our results demonstrate how perceptual behaviors are shaped and dynamically modulated in the mammalian cortex.
Bodian Seminar: Paul R. MacNeilage PhD
Department of Psychology & Institute for Neuroscience
University of Nevada, Reno