Events

Bodian Seminars are scheduled for every Monday at 4 p.m. If there is not a specific date listed below, then that date is open. Please contact us to schedule a seminar for an open date.

Feb
25
Mon
Bodian Seminar: Sridevi V. Sarma, Ph.D.
Feb 25 @ 4:00 pm – 5:00 pm

Bodian Seminar

Sridevi V. Sarma, Ph.D.

Associate Professor

Institute of Computational Medicine

Johns Hopkins University

Risk-taking bias in human decision-making is encoded

via a right-left brain push-pull system

A person’s decisions vary even when options stay the same, like when a gambler changes bets despite constant odds of winning. Internal bias (e.g., emotion) contributes to this variability and is shaped by past outcomes, yet its neurobiology during decision-making is not well understood. To map neural circuits encoding bias, we administered a gambling task to 10 participants implanted with intracerebral depth electrodes in cortical and subcortical structures. We predicted the variability in betting behavior within and across patients by individual bias, which is estimated through a dynamical model of choice. Our analysis further revealed that high-frequency activity increased in the right hemisphere when participants were biased towards risky bets, while it increased in the left hemisphere when participants were biased away from risky bets. Our findings provide the first electrophysiological evidence that risk-taking bias is a lateralized push-pull neural system governing counterintuitive and highly variable decision-making in humans.

Mar
18
Mon
Bodian Seminar: Long Ding, Ph.D.
Mar 18 @ 4:00 pm – 5:00 pm

Bodian Seminar:

Long Ding, Ph.D.

Research Assistant Professor

Department of Neuroscience

University of Pennsylvania

The caudate nucleus and reward-based visual decisions

Decision making is a complex process that interprets sensory information within the context of reward contingency, task goal and intrinsic bias, etc. How and where this process is implemented in the brain remain unclear. The basal ganglia have been shown to contribute causally to reward-based economic decisions and to noisy sensory evidence-based perceptual decisions, leading to the hypothesis that sensory and reward information may be combined within the basal ganglia to support decision formation. In my talk, I will present our new results on how the caudate nucleus encodes combined signals at the single-neuron level and how disruption of caudate activity influences decision performance. These results further support the idea that the basal ganglia are a key player in the complex decision process.

Apr
17
Wed
Bodian Seminar: Uta Noppeney, Ph.D.
Apr 17 @ 4:00 pm – 5:00 pm

Bodian Seminar:

Uta Noppeney, Ph.D.

Professor

Computational Neuroscience

Cognitive Robotics Centre

University of Birmingham

United Kingdom

TBA

May
20
Mon
Bodian Seminar: Soohyun Lee, Ph.D.
May 20 @ 4:00 pm – 5:00 pm

Bodian Seminar:

Soohyun Lee, Ph.D.

Investigator

Unit on Functional Neural Circuits

NIMH

TBA