The Zanvyl Krieger Mind/Brain Institute

Joni Wallis, Ph.D.Professor, Dept. of PsychologyUniversity of California, Berkeley Hippocampal contributions to value-based decision-making People with damage to orbitofrontal cortex (OFC) have specific problems making decisions, whereas their other cognitive functions are spared. Neurophysiological studies have shown that OFC neurons fire in proportion to the value of anticipated outcomes. Thus, a central role of OFC […]

Matthew Chafee, Ph.D.Professor, Department of NeuroscienceUniversity of Minnesota Medical School Cognitive flexibility and neural communication patterns in monkey prefrontal networks Synaptic interactions mediate the exchange of information between neurons that is perhaps the most direct biological correlate of computation in brain networks.   To capture these dynamics, our lab records spiking activity in groups of neurons […]